An urticaria antihistamine is a drug that counteracts the effects of
histamines that cause urticaria. However,
urticaria
antihistamines do not treat the underlying causes of urticaria. They only
provide temporary relief from the itching or burning sensation and are not
considered to be a permanent
urticaria treatment.
Histamines are released by the mast cells, which are widespread throughout the
skin. When these mast cells are triggered by certain stimuli, they release
histamines into the adjacent area of the skin. These histamines then cause
rashes, itching, burning sensations, swelling, and other problems according to
the nature of the stimulus. These skin problems are called urticaria.
There are four major types of histamines defined by medical science: H1, H2, H3,
and H4. Furthermore, H3 and H4 antihistamines are not used in common clinical
practice and are merely used for experimental purposes. H1 and H2 antihistamines
are inverse agonists. H2 antihistamines are usually used to reduce the secretion
of gastric acid and to treat other gastrointestinal conditions, including peptic
ulcers and gastroesophageal reflux disease.
H1 antihistamines are used to treat allergic reactions, including different
types of urticaria. Other uses of H1 antihistamines include reducing local
inflammation that occurs due to various conditions, such as insect stings, even
if there is no allergic reaction. Some antihistamines can cause drowsiness;
therefore, activities that require mental and physical vigilance should be
avoided after taking them.
Remember that antihistamines are used to provide the patient temporary relief,
and patients should avoid their permanent use, as some of them are addictive.
P.S. (from
Dr. Gary M. Levin, M.D. & Surgeon)
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